The Influence of Fucoxanthin Immobilized on Porous Aluminum-Silicon Carrier Surface on the Functional Activities of Immunocytes in Mice

Fucoxanthin is a natural carotenoid obtained from seaweed which exhibits antioxidant properties. This research aimed to assess whether fucoxanthin, immobilized on aluminum-silicon carrier particles, has toxic effect immune cells. The viability, proliferation, nitric oxide production and myeloperoxidase activity of thymocytes splenocytes mice in vitro were studied. It was shown that increased the survival rate proliferation mature immunocytes (splenocytes) after 24 hours exposure naïve (thymocytes) when exposed for 120 hours. In terms myeloperoxidase, cells not affected by fucoxanthin particles. results indicated particles an carrier, did have mouse immunocytes.
 Keywords: Cylindrotheca closterium, γ-aluminum oxide, polydimethylsiloxane, thymocytes, splenocytes,